SR9009, also known as Stenabolic, is an agonist of Rev-ErbA (i.e., increases the constitutive repression of genes regulated by Rev-ErbA) with a half-maximum inhibitory concentration (IC50) = 670 nM for Rev-ErbAα and IC50 = 800 nM for Rev-ErbAβ.
Activation of Rev-ErbA-α by SR9009 in mice increases exercise capacity by increasing mitochondria counts in skeletal muscle. This non-SARM can increase endurance. Stenabolic is not a SARM, but a REV-ERB which means it affects the metabolism
Those who use SARMs and SARM-like compounds commonly follow 8 week cycles for lean muscle gain and strength enhancement then take the following 8 weeks off. Recommended daily dose for SR9009 is anywhere from 10-30mg for optimal results.
12 April 2022