Andarine (developmental code name S-4) is an investigational selective androgen receptor modulator (SARM). Developed for treatment of conditions such as muscle wasting, osteoporosis and benign prostatic hypertrophy, using the nonsteroidal antiandrogen bicalutamide as a lead compound. It can help to minimise muscle wasting, promote strength, and gain lean muscle. Those who use SARMs and SARM-like compounds commonly follow 8 week cycles for lean muscle gain and strength enhancement then take the following 8 weeks off. The daily optimum dose for S-4 is 25mg daily.